Three genes predict success of naltrexone in alcohol dependence treatment

Of patients who seek treatment for alcohol use disorder, 60% to 80% relapse within a year. Taking the medication naltrexone reduces this number by a third. Yet only 20% of patients receive medications because they do not work well for everyone. Medical University of South Carolina researchers report in Alcoholism: Clinical and Experimental Research that measuring variants in just three brain genes makes it is possible to predict who will benefit from naltrexone.