Army and Illinois researchers design, test protein that may lead to COVID-19 therapeutic

Army scientists have demonstrated that a “decoy” receptor developed by University of Illinois researchers has potent neutralizing activity against SARS-CoV-2–activity that is on par with the best neutralizing antibodies identified to date. Furthermore, they found that the decoy receptor not only neutralizes SARS-CoV-2, but also acts to neutralize SARS-CoV-1, a closely related virus that uses the same cellular receptor. Results appear in the Aug. 4 online edition of Science.