Gut microbes shape our antibodies before we are infected by pathogens

Because the microbiota is so complex, containing hundreds of different bacterial species, it is not known how the presence of microbes in the intestine shaped the antibodies that are present even before we are challenged by an infection. Researchers at the Department for BioMedical Research (DBMR) of the University of Bern and the Inselspital, University Hospital Bern, have now shown how these beneficial microbes reprogram the repertoire of white blood B cells that produce antibodies and how this helps counter infections.