Amyloid formation in the International Space Station

The collaborative research team of Japan using the International Space Station (ISS) successfully characterized Alzheimer’s disease-related amyloid fibril formation under microgravity conditions. Their findings demonstrated that amyloid fibril formation on the ISS is significantly slower than that on the Earth. Moreover, microgravity promoted the formation of distinct morphologies of amyloid fibrils. The project highlights the utility of the ISS as an ideal experimental environment for investigating amyloid formation mechanisms without uncontrollable perturbations caused by gravity.