Experts clarify subtypes of multiple sclerosis to improve care and clinical trials

An international committee has clarified previously published descriptors of courses of MS and disease activity. MS subtypes are consensus definitions rather than pathologically defined phenotypes, and easily misconstrued. The clarification was prompted in part by differences in specified indications for MS therapies recently approved by the FDA and EMA. The goal is to improve care and refine the selection of clinical trial participants so that trial outcomes can better inform clinical care.