A Japanese research group analyzed the pathophysiology of myelodysplastic syndrome (MDS), a blood cancer that presents often in the elderly, and found the presence of transcription factor RUNX3, thereby revealing a cancer growth function for what had been considered be a tumor suppressor. Additional analyses of human MDS cells and model mice found an abnormal gene expression mechanism linked to the onset of cancer, and confirmed RUNX3 as a potential therapeutic target.
- Oncotarget: Evaluation of cellular alteration & inflammatory profile of cells
- Cause of Alzheimer’s disease traced to mutation in common enzyme
- Elkhorn coral actively fighting off diseases on reef, study finds
- Mary Ann Liebert, Inc. to publish Journal of Correctional Health Care
- Exploring the source of stars and planets in a laboratory