The microbiome controls immune system fitness

Working alongside colleagues in Mainz, Bern, Hannover and Bonn, researchers from Charité — Universitätsmedizin Berlin, the Berlin Institute of Health (BIH) and the German Rheumatism Research Center Berlin (DRFZ) were able to show how the microbiome helps to render the immune system capable of responding to pathogens. If absent, relevant mediators are not released, resulting in a failure to activate metabolic processes in certain immune cells, according to the researchers’ report, published in Cell*.