Targeting depression: Researchers ID symptom-specific targets for treatment of depression

For the first time, physician-scientists at Beth Israel Deaconess Medical Center have identified two clusters of depressive symptoms that responded to two distinct neuroanatomical treatment targets in patients who underwent transcranial magnetic brain stimulation (TMS) for treatment of depression. The team’s findings shed new light on the brain circuitry underlying specific symptoms of depression and may facilitate personalized TMS therapy for depression and other psychiatric or neurological disorders.