By analysing genomic data from worms, scientists detailed how mutations are caused by a combination of DNA damage and inaccurate repair. This shows that a single DNA-damaging agent can generate a multitude of mutational signatures depending on the repair mechanisms involved in fixing the original damage. The research could help pinpoint the causes of mutations found in the genomes of cancer patients and healthy individuals.
- Predictive value of blood pressure, heart rate, and blood pressure/heart rate ratio in a Chinese subpopulation with vasovagal syncope
- Risk factors for intraoperative pressure injury in aortic surgery
- ECMO/CRRT in the treatment of critically ill SARS-CoV-2 pneumonia patients
- Regulating the ribosomal RNA production line
- New technique builds super-hard metals from nanoparticles