In this report, a team of researchers lead by Dr. Grigoris Zoidis at the National and Kapodistrian University of Athens (Athens, Greece), in collaboration with researchers at the Ruder Boskovic Institute (Zagreb (Croatia), and the London School of Hygiene and Tropical Medicine (London, United Kingdom) have attempted to extend the structure-activity relationship (SAR) analysis of a number of lipophilic guanylhydrazone analogues with respect to in vitro growth inhibition of T. brucei and T. cruzi.
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