Connecting the dots between heart disease, potential for worse COVID-19 outcomes

People with certain heart diseases may be more susceptible to worse outcomes with COVID-19, but the reason why has remained unknown. New research from Mayo Clinic indicates that in patients with one specific type of heart disease ? obstructive hypertrophic cardiomyopathy (HCM) ? the heart increases production of the ACE2 RNA transcript and the translated ACE2 protein.