TGen adds to international studies identifying cells susceptible to SARS-CoV-2 infection

Two studies involving hundreds of scientists, including a human geneticist at TGen, suggest that cells in the nasal passage shaped like champagne glasses — goblet cells — may play a significant role in the spread of COVID-19. One published April 23 in Nature Medicine and another published April 22 in Cell, indicate goblet cells highly express a receptor enzyme called ACE2 that binds to the spikes covering the outer surface of SARS-CoV-2, the virus that causes COVID-19.