Preventing metastasis — An antibody with therapeutic potential

A receptor in the cell layer that lines the blood vessels from the inside stimulates both the formation of new blood vessels in tumors and metastasis. Scientists at the German Cancer Research Center in Heidelberg (DKFZ) and the Mannheim Medical Faculty of the University of Heidelberg have succeeded in blocking this receptor with an antibody to thus prevent the growth of metastases in mice with breast or lung cancer.