Researchers delay onset of amyotrophic lateral sclerosis (ALS) in laboratory models

Scientists have delayed the onset of amyotrophic lateral sclerosis (ALS) in laboratory models, leaving them cautiously optimistic that the result, combined with other clinical advances, points to a potential treatment for ALS in humans. The researchers targeted neurons in the brain’s motor cortex with an engineered protein that prevented their degeneration and delayed the onset of symptoms such as hardening of the neuron’s myelin sheath, weight loss and a deterioration in motor skills.